AACN to present Flame of Excellence Award to VCU researcher The American Association of Critical-Care Nurses will show the Flame of Excellence Award to noted researcher and educator Mary Jo Grap, RN, PhD, FAAN, professor, School of Nursing, Virginia Commonwealth University, Richmond. Grap shall receive the award at the 2011 National Teaching Institute & Crucial Care Exposition, Chicago, 30-May 5 April. The Flame of Excellence Award honors sustained contributions to acute and critical care nursing at a high level and with wide reach. She helped to build up and check the Richmond Agitation Sedation Level, considered the to begin a better ‘second-generation’ sedation evaluation tool.For the ACCEPT Research Group: Assessment of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis Psoriasis is a chronic, inflammatory skin disease affecting approximately 2 percent of the world’s population.1,2 Therapeutic agents used for the management of psoriasis commonly target the underlying inflammation. Immunosuppressive agents such as for example methotrexate and cyclosporine possess proved effective in the treatment of psoriasis.3 Biologic agents that selectively block steps in the inflammatory cascade have got provided extra therapies for psoriasis and have led to a better knowledge of its immunologic and pathophysiological basis.10-12 More recently, interleukin-23 and interleukin-12, cytokines that induce naive CD4+ lymphocytes to differentiate into type 1 helper T cells and type 17 helper T cells , respectively, have been identified as key mediators of psoriasis.13-18 A new class of biologic agents that block both interleukin-12 and interleukin-23 provides been shown to work for the treatment of psoriasis.