The research was supported by the National Institutes of Health.

The research was supported by the National Institutes of Health, the Lucile Packard Foundation for Children ‘s Health, the Damon Runyon Cancer Foundation, the California Institute for Regenerative Medicine, the Human Frontier Science Program, the European Molecular Biology Organization, the Fonds supported de la Recherche Scientifique, the Leon Fredericq Foundation and the Leukemia and Lymphoma Society.

She wants to find out why differentiated myeloid cells can not proliferate inappropriately, since they too are missing Rb family members.. Viatour and Sage devised a way to inhibit, or knock out, the function of all three proteins in adult mice. You genetically animals in which the p107 gene is deleted and the pRb and p130 genes designed cleaved flanked by pieces of DNA that are recognized and by a specialized protein called the Cre recombinase. That is, the entire blood system without functional Rb family members – If blood stem cells, the recombinase snips from Rb and p130 gene, so that these stem cells and their progeny expressed.

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